Endocrine Abstracts

Objective: Thyroid nodules are the most common thyroid disease and preoperative differentiation of benign and malignant lesions is an important diagnostic purpose. In about 1/3 cases FRA and cytological examination shows indeterminate diagnosis. Deregulation of miRNA expression has been described in a variety of tumors, including thyroid cancer. The aim of our study is to evaluate the association between miRNAs expression and risk of thyroid cancer in patients with thyroid nod...

Introduction: We report the clinical presentation, immunohistochemistry, imaging, histopathology, treatment and outcome of a patient with ACTH-secreting tumour of liver.Case report: Cushing’s Syndrome due to ectopic ACTH production is uncommon and due to neuroendocrine tumour of liver is extremely rare. We discuss the case of a 27-year-old female who initially presented with vague, non-specific symptoms, such as general and muscle weakness, weight g...

Introduction: Ectopic ACTH syndrome (EAS) is a rare cause of ACTH-dependent endogenous hypercortisolism.Objective: The objective of this study was to analyse the clinical, biochemical, and radiological features, management, and treatment outcome of patients with EAS.Design: It was a retrospective case-record study of 52 patients with EAS.Materials and methods: Clinical, biochemical, and radiological features ...

Objective: Ectopic adrenocorticotropic hormone (ACTH-ectopic) syndrome (EAS) is a rare cause of ACTH-dependent endogenous hypercortisolism. The objective of this study was to analyze the clinical, biochemical, and radiological features, management, and treatment outcome of patients with EAS.Methods: It was a retrospective case-record study of 47 patients with EAS. Clinical, biochemical, and radiological features and response to therapy and survival rate ...

Objective: To report a case of Cushing’s syndrome due to ectopic ACTH secretion and to evaluate role of somatostatin analogues for the localization and postoperative treatment of adrenocorticotropin-secreting bronchial carcinoid tumor.Methods: We describe the clinical presentation of our case and discuss its management.Results: A 57-year-old woman presented with symptoms and physical findings strongly suggestive of Cushing syn...